 | Current Issue:January 2003, Volume 3, Issue 1: "On the Chemical Causation of Methyl Deficiency and its Attendant Pathologies" Text Version, PDF Version, Past Issues Subscribe to the Regulatory Research Perspectives (RRP) E-Mail List |
Issue 1 of Volume 3 of the Regulatory Research Perspectives: Impact on Public Health. Several lines of evidence indicate that physiological methyl group deficiency and abnormal DNA methylation are involved in the etiology of several pathological processes. This review summarizes the evidence that pathologies such as cancer, pancreatic toxicity, atherosclerosis, birth defects and neurotoxicity may be related to these deficiencies.
The objective of the Regulatory Research Perspectives journal is to provide a vehicle for FDA scientists to communicate important scientific information to each other with the hope of generating collaborations and to communicate to the global community science that is important to the Agency. It is hoped that each center will submit manuscripts for publication through their respective editorial board members. Initially, we plan to publish quarterly. See the "Instructions to Authors" provided on this site.
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Past Issues
| Date | Title | Text Version | PDF Version |
|---|---|---|---|
| May 2002 | Development of Quantitative Structure-Activity Relationships (QSARs) and Their Use for Priority Setting in the Testing Strategy of Endocrine Disruptors | text version | pdf version |
| November 2001 | Developing Methods of Genetic Analysis to Improve Cancer Risk Assessment | text version | pdf version |
| July 2001 | Human Health Impact and Regulatory Issues Involving Antimicrobial Resistance in the Food Animal Production Environment | text version | pdf version |
