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What is carpal tunnel syndrome?

Some people might think that carpal tunnel syndrome is a condition of the information technology age, born from long hours of computer keyboarding. But carpal tunnel syndrome is nothing new. Evidence of people experiencing symptoms of carpal tunnel syndrome occurs in medical records dating back to the beginning of the 20th century.

Bounded by bones and ligaments, the carpal tunnel is a narrow passageway — about as big around as your thumb — on the palm side of your wrist. This tunnel protects a main nerve (median nerve) to your hand and nine tendons that bend your fingers. Pressure placed on the nerve produces the numbness, pain and, eventually, hand weakness that characterize carpal tunnel syndrome.

Fortunately, for most people who develop carpal tunnel syndrome, proper treatment usually can relieve the pain and numbness and restore normal use of the wrists and hands.

Signs and symptoms

Carpal tunnel syndrome typically starts gradually, with a vague aching in your wrist that can extend to your hand or forearm. Other common signs and symptoms include:
Causes

The cause of carpal tunnel syndrome is pressure put on the median nerve. The median nerve is a mixed nerve, meaning it has a sensory function and also provides nerve signals to move your muscles (motor function). The median nerve provides sensation to your thumb, index finger, middle finger and the middle finger side of the ring finger. Pressure on the nerve can stem from anything that reduces the space for it in the carpal tunnel. Causes might include anything from bone spurs to the most common cause, which is swelling or thickening of the lining and lubricating layer (synovium) of the tendons in your carpal tunnel.

The exact cause of the swelling usually isn't known, but a variety of conditions and factors can play a role. Some examples include rheumatoid arthritis, certain hormonal disorders — such as diabetes, thyroid disorders and menopause — fluid retention due to pregnancy, or deposits of amyloid, an abnormal protein produced by cells in your bone marrow.

Repetitive flexing and extending of the tendons in the hands and wrists, particularly when done forcefully and for prolonged periods without rest, also can increase pressure within the carpal tunnel. Injury to your wrist can cause swelling that exerts pressure on the median nerve.

Physical characteristics also may play a role. It may be that your carpal tunnel is more narrow than average. Carpal tunnel syndrome may be associated with people who have square wrists, where the width and thickness are about the same, versus the more common rectangular wrist. Other less common causes include a generalized nerve problem or pressure on the median nerve at more than one location.

Menopause
Amyloidosis

Risk factors

Some studies suggest that carpal tunnel syndrome can result from overuse or strain in certain job tasks that require a combination of repetitive, forceful and awkward or stressed motions of your hands and wrists. Examples of these include using power tools — such as chippers, grinders, chain saws or jackhammers — and heavy assembly line work, such as occurs in a meatpacking plant. Some studies have also indicated that typing or computer use may cause carpal tunnel syndrome, but the scientific evidence for this is weak. For example, a study published June 2001 in the journal Neurology found that computer users experienced carpal tunnel syndrome at frequencies comparable to estimates for the general public.

Although it's not clear which activities can cause carpal tunnel syndrome, if your work or hobbies are hand-intensive — involving a combination of awkward, repetitive wrist or finger motion, forceful pinching or gripping and working with vibrating tools — you may be at higher risk of developing the condition.

Women are three times as likely as men are to develop carpal tunnel syndrome. The incidence in women peaks between the ages of 45 and 54, and the risk of carpal tunnel syndrome also increases with age in men.

Certain health conditions can increase your risk, including some thyroid problems, diabetes, obesity and rheumatoid arthritis. Women who are pregnant, taking oral contraceptives or going through menopause also are at increased risk, most likely due to hormonal changes. Fluid retention may be a cause of carpal tunnel syndrome during pregnancy. Fortunately, carpal tunnel syndrome related to pregnancy almost always improves after childbirth. People who smoke cigarettes may experience worse symptoms and slower recovery from carpal tunnel syndrome than nonsmokers do.

Diabetes
Obesity
Rheumatoid arthritis
Menopause

When to seek medical advice

If signs and symptoms that you think might be due to carpal tunnel syndrome interfere with your normal activities — including sleep — and they persist, see your doctor. If you leave the condition untreated, nerve and muscle damage can occur

Screening and diagnosis

Your doctor will most likely want to review your signs and symptoms to find out where they're located. One diagnostic key is that the median nerve doesn't provide sensation to your little fingers. Another clue is the timing of the symptoms. Typical times when you might experience symptoms due to carpal tunnel syndrome include while holding a phone or a newspaper, gripping a steering wheel, or sleeping. Your doctor will also want to test the feeling in your fingers and the strength of the muscles in your hand, because these can be affected by carpal tunnel syndrome. Pressure on the median nerve at the wrist, produced by either bending the wrist, tapping on the nerve or simply pressing on the nerve, can bring on the symptoms in many people.

If you have signs and symptoms of carpal tunnel syndrome, your doctor may recommend the following diagnostic tests: These tests are also useful in checking for other conditions that might mimic carpal tunnel syndrome, such as a pinched nerve in your neck. Your doctor may recommend that you see a rheumatologist, neurologist, hand surgeon or neurosurgeon — depending on whether you have additional signs or symptoms of other medical disorders or need specialized treatment.

Treatment

Conservative and early treatments include nonsteroidal anti-inflammatory drugs (NSAIDs), which can help control pain and may help if you have an associated inflammatory condition. If no inflammatory condition is involved, NSAIDs are unlikely to help relieve the symptoms of carpal tunnel syndrome.

Simply taking more frequent hand-rest breaks can help. And a splint that holds your wrist still while you sleep can help relieve nighttime symptoms of tingling and numbness. Applying cold packs can help reduce swelling if you have inflammation. Your doctor might also inject the affected area with a corticosteroid, a medication that suppresses inflammation and which may provide some relief from symptoms. Or your doctor may have you take oral corticosteroids.

Generally, these conservative treatments are more effective if you have only mild nerve impairment.

Nonsteroidal anti-inflammatory drugs (NSAIDs)
Steroid use: Balancing the risks and benefits

When the pain or numbness of carpal tunnel syndrome persists, an operation may be the best option. Your surgeon may use one of a few accepted techniques. But in all accepted surgical procedures, your doctor cuts the ligament pressing on your nerve. At times, surgery can be done using an endoscope, a telescope-like device with a tiny television camera attached to it that allows your doctor to see inside your carpal tunnel and perform the surgery through small incisions in your hand or wrist. In other cases, surgery involves making an incision in the palm of your hand over the carpal tunnel and releasing the nerve. In most people surgery results in marked improvement, but some residual numbness, pain, stiffness or weakness may persist.


A May 2001 study, published in Arthritis and Rheumatism, reported that out of 181 people who had undergone carpal tunnel release, two-thirds said they were completely or very satisfied with the outcome of their surgery at six, 18 and 30 months after the procedure. Some variables that were associated with lower levels of satisfaction included alcohol use, lower mental and physical health status before surgery, and exposure to repetitive, forceful activity — not including keyboard use.

After surgery, your doctor may tell you that limited use of your hand and wrist is OK within a few days. However, it may take from several weeks to as long as a few months before you have unrestricted use of your hand and wrist. If surgery appears to be the best alternative for relieving your symptoms or preventing further muscle atrophy, be sure to talk with your surgeon about the procedure that will work best for you and with your plans to return to your previous activity levels, both at work and at home.

If carpal tunnel syndrome results from an inflammatory arthritis, such as rheumatoid arthritis, then treating the underlying condition generally also reduces the carpal tunnel syndrome symptoms. This may not be the case with all underlying conditions, such as thyroid conditions or diabetes.

Prevention

There are no proven strategies to prevent carpal tunnel syndrome, but to protect your hands from a variety of ailments, take the following precautions:
Self-care

Quick breaks, stretching, aspirin or other over-the-counter NSAIDs may relieve your symptoms temporarily.

You might also want to try wearing a wrist splint at night and avoid sleeping on your hands to help ease the pain or numbness in your wrists and hands. The splint should be snug but not tight. If pain, numbness or weakness recurs and persists, see your doctor.


Coping skills

If you experience chronic pain or can't use your hands as before, you may become depressed or suffer from low self-esteem. In addition, if your hand symptoms are caused or worsened by your current profession or leisure activities, you may face the tough decision of switching careers or giving up hobbies. You may also feel that you aren't actively contributing to your family if you can't drive a car or perform ordinary household tasks.

Support groups for people with carpal tunnel syndrome can help you find out more information about your condition plus offer advice and solace. Stress management and relaxation techniques may also help you deal with the psychological and emotional issues that may accompany carpal tunnel syndrome.

On the job with arthritis: How to make it work
Manage life’s stresses
Support groups for chronic pain

Complementary and alternative medicine

Yoga and other relaxation techniques may help with chronic pain that occurs with some muscle and joint conditions. Yoga postures designed for strengthening, stretching and balancing each joint in the upper body, as well as the upper body itself, may help reduce the pain and improve the grip strength of people with carpal tunnel syndrome.

Other options for treatment involve special types of physical therapy. Many of the methods used for carpal tunnel syndrome include heat, massage, chiropractic and osteopathic manipulation, and water therapy (hydrotherapy). Ultrasound treatments may be used, but have had variable results in studies. In 1997, the National Institutes of Health released a consensus statement acknowledging that acupuncture also may be useful for treating the symptoms of carpal tunnel syndrome. However, magnet therapy, laser acupuncture and chiropractic care haven't provided the same benefits in controlled trials.

You may have to experiment to find a treatment that works for you. Still, always check with your doctor before trying any complementary or alternative treatment.

June 3, 2003

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