Cancer Genetics Branch

Susceptibility to certain cancers is inherited, while many other cancers result from genetic changes arising throughout life. Using the research tools of modern molecular biology, investigators in the Cancer Genetics Branch seek to define the genetic changes involved in the occurrence and progression of cancer.

The branch is currently pursuing a range of experimental studies, such as:

• Pinpointing the inherited mutations leading to familial malignant melanoma, prostate and breast cancers.
• Finding the genes that convey malignancy (e.g., metastasis and drug resistance) to cancer cells.
• Developing and applying technologies, such as cDNA microarray technology, for genome-wide scans of genetic variation and expression.

Principal Investigators

Paul S. Meltzer, M.D., Ph.D.
Acting Chief and Senior Investigator, Cancer Genetics Branch
Head, Molecular Cytogenetics Section

Raman B. Sood, Ph.D.
Associate Investigator, Cancer Genetics Branch

Project Web Sites:
cDNA Microarray Project
Includes protocols, analysis, resources and related links.

Tissue Microarray Project

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