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How can we tell if someone is abusing or addicted to drugs?

Diagnostic and Statistical Manual - III - R
[DSM-III-R is not currently used but has historical utility.] At least three of the following are necessary; some of the symptoms of the disturbance must have persisted for at least one month or have occurred repeatedly over a longer period of time:

Diagnostic and Statistical Manual - IV

A maladaptive pattern of substance use leading to clinically significant impairment or distress as manifested by three (or more) of the following, occurring at any time in the same 12-month period:

International Classification of Diseases - 10
[ICD-10 research criteria differ from the clinical diagnostic quidelines listed here.] Three or more of the following must have been experienced or exhibited at some time during the previous year: